qPCR—25 years old but still a matter of debate

Lymphadenectomy for gastric cancer: still a matter of debate?

BACKGROUND For more than a century the extent of surgical treatment of gastric cancer is a matter of debate. Through experience, evaluation and research, the outcome of gastric cancer has improved. Many aspects are of influence of outcome, but only a radical resection can offer long-term outcomes. In this review, we will discuss the history and current status of the extent of lymph node dissect...

Antioxidant Therapy in Cardiovascular Diseases: Still a Matter of Debate

Reactive Oxygen Species (ROS) are highly reactive chemical species, which are responsible for oxidative stress inside the cell. They are mainly generated in vascular cells by NAD(P)H oxidases, uncoupled endothelial nitric oxide (NO) synthase, and other enzymatic sources, or as a byproduct of mitochondrial respiration. Imbalanced production of ROS lead to exacerbation of pathophysiological proce...

50 Years Old and Still Alive: Eigenproblems

Q Fever: An Old but Still a Poorly Understood Disease

Q fever is a bacterial infection affecting mainly the lungs, liver, and heart. It is found around the world and is caused by the bacteria Coxiella burnetii. The bacteria affects sheep, goats, cattle, dogs, cats, birds, rodents, and ticks. Infected animals shed this bacteria in birth products, feces, milk, and urine. Humans usually get Q fever by breathing in contaminated droplets released by in...

Traffic accidents in Iran, a decade of progress but still challenges ahead

  Iran has had incremental incidence of traffic accident mortality since introduction of mechanization about a century ago. But the newest data from Iran show decrease in the absolute number of deaths, death per 10,000 vehicles and death per 100, 000 populations. Despite its huge impact on health and economy, research in the field of traffic crashes is still scant and there are still deficienci...